Polysulfated Glycosaminoglycan

“This page provides important general information for pet owners whose animals have been prescribed Polysulfated Glycosaminoglycan during a consultation by Dr Noor.”

Key Information

Note: This handout is meant to address questions people often ask. It is not a complete guide to this medication. It also does not replace medical guidance from your veterinary care team.

Description

This medication is used to help protect joints. It is supplied as a liquid that is given by injection.

Other common names

  • Adequan Canine
  • PSGAG

Uses of Polysulfated Glycosaminoglycan

Approved uses in animals:

  • This medication is used in dogs to help manage signs linked with arthritis.

Your veterinarian may also choose to use this medication in other animal species or for other purposes.

Before this medication is given

No medication is completely safe for every patient. Talk with your veterinarian about:

  • Any medicines or supplements your animal is currently receiving
  • Any health problems your animal has now, or has had before
  • Any unwanted reactions your animal has had with medicines in the past
  • The possible risks of using this medication if your animal is pregnant or nursing

Warnings for animals

Do not use this medication in animals:

  • That have an allergy to this medication
  • That have problems with abnormal bleeding

Use extra care in animals:

  • That have liver disease or kidney disease

Some animal sports or competitions do not allow certain medications. If your animal competes, confirm the rules while your animal is receiving this medication.

Warnings for humans

  • After you handle any medication, wash your hands.
  • To reduce the chance of a needle injury, throw away used needles right after use. Do not put the cap back on the needle.
  • A needle injury can cause pain and infection. If you are stuck by a needle, contact your doctor.

How do I give this medication?

Give this medication exactly the way your veterinarian directed. Always follow the directions printed on the prescription label.

This medication is given by injection either:

  • Into a muscle, or
  • Under the skin

The liquid should look clear. Its color can be colorless or slightly yellow. Do not use it if it looks cloudy, has changed color, or if you see crystals or any particles in it.

Side effects

Common — call your veterinarian if any of the following are serious, keep happening, or get worse over time:

  • Vomiting
  • Eating less than usual
  • Loose stools or diarrhea
  • Low energy
  • Soreness or pain where the injection was given

Severe — stop giving the medication and contact your veterinarian right away if you notice:

  • Bruising or any signs of bleeding

Also contact your veterinarian if you see bleeding or bruising that is not expected.

How will I know it's working?

This medication may begin to help after several doses. Improvement is usually gradual as the medication reaches its full effect.

It can take up to a few weeks to know whether the treatment is helping.

Contact your veterinary clinic if your animal’s symptoms get worse or do not get better.

How long will the medication effects last?

After the final dose, the effects may continue for a few days to a few weeks.

How long do I give it for?

The length of treatment can vary. Follow the plan your veterinarian provided.

Overdose

Too much of this medication may lead to bruising and other bleeding-related signs. If you see or think an overdose has happened, call your veterinarian or an animal poison control service (a consultation fee may apply):

Have the medication container or its label available if you can.

Missed dose

If you miss a dose, give it as soon as you can. After that, go back to the usual dosing schedule.

Storage

  • Keep this medication at room temperature.
  • Store all medications where children and animals cannot reach them.
  • Throw away this medication 28 days after the first time the vial is punctured, or after 10 punctures, whichever happens first.

Disposal

  • If possible, bring unused medication to a local medication “take-back” program.
  • If that is not available, dispose of it in the regular household trash.

Questions?

Speak with your veterinarian.

“Disclaimer: The information on this page is provided as general educational material only. Every animal’s health situation is unique, and treatment decisions must be based on a full veterinary assessment. Always follow the specific instructions given during your consultation, and contact the prescribing veterinarian if you have any concerns.”

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